Prenatal developmental toxicity of crocus sativus (saffron) in wistar rats

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Hepatoprotective effect of Crocus sativus (saffron) petals extract against acetaminophen toxicity in male Wistar rats

OBJECTIVES Acetaminophen (APAP) toxicity is known to be common and potentially fatal. This study aims to investigate the protective effects of hydroalcoholic extract, remaining from Crocus sativus petals (CSP) against APAP-induced hepatotoxicity by measuring the blood parameters and studying the histopathology of liver in male rats. MATERIALS AND METHODS Wister rats (24) were randomly assigne...

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Hepatoprotective effect of Crocus sativus (saffron) petals extract against acetaminophen toxicity in male Wistar rats

Objectives: Acetaminophen (APAP) toxicity is known to be common and potentially fatal. This study aims to investigate the protective effects of hydroalcoholic extract, remaining from Crocus sativus petals (CSP) against APAP-induced hepatotoxicity by measuring the blood parameters and studying the histopathology of liver in male rats. Materials and Methods: Wister rats (24) were randomly assigne...

متن کامل

hepatoprotective effect of crocus sativus (saffron) petals extract against acetaminophen toxicity in male wistar rats

objectives: acetaminophen (apap) toxicity is known to be common and potentially fatal. this study aims to investigate the protective effects of hydroalcoholic extract, remaining from crocus sativus petals (csp) against apap-induced hepatotoxicity by measuring the blood parameters and studying the histopathology of liver in male rats. materials and methods: wister rats (24) were randomly assigne...

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Safety evaluation of saffron (Crocus sativus) tablets in healthy volunteers.

Saffron (Crocus sativus) stigma tablets were evaluated for short-term safety and tolerability in healthy adult volunteers. The study was a double-blind, placebo-controlled design consisting of a 1 week treatment of saffron tablets. Volunteers were divided into 3 groups of 10 each (5 males and 5 females). Group I received placebo; groups 2 and 3 received 200 and 400mg saffron tablets, respective...

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Antitumor Effect of Saffron (Crocus sativus L.): Overview and Perspectives

From ancient times, saffron dried stigmas of Crocus sativus L. is widely used as a drug against different human diseases. In the beginning of 1990 ́s scientific literature reported for the first time the antitumor activity of saffron. During the last decade different laboratories of the world (including ours) have accumulated sufficient scientific evidence to suggest that saffron, and its main i...

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ژورنال

عنوان ژورنال: International Journal of Pharmacology and Toxicology

سال: 2014

ISSN: 2310-2985

DOI: 10.14419/ijpt.v2i2.3035